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Canine Coat and Nose Color Testing


C128-Canine Coat and Nose Color Test
Eurasier

DNA TEST

Eurasiers are a breed developed in the 1960’s by careful breeding of the German Wolfspitz, Chow Chow, and Samoyed. Many color patterns exist within the breed, though the inheritance patterns are relatively straightforward and are the result of alleles at only two genes: A or ASIP and E or MC1R. DNA tests are available to identify all four A alleles and all three E alleles.

Most of the patterns seen in Eurasiers are caused by the alleles of the ASIP locus. Eurasiers are one of the only breeds that have all four ASIP alleles: ay > aw > at > a. The ay allele produces a fawn pattern that is mostly red with some black hairs or black-tipped red hairs. The wolf sable pattern, caused by the aw allele, has banded hairs alternating between black and red/cream along the hair shaft. The at  allele produces a black-and-tan phenotype with black pigment over the body of the dog and red pigment on the legs, cheeks, eyebrows, chest, and beneath the tail. The final allele of ASIP, a, produces a solid black phenotype. This allele is normally only seen in herding-type breeds, but the inclusion of the Samoyed (which are all ee and aa) introduced the allele to the Eurasier as well.

Three alleles of the MC1R locus are present in Eurasiers: EM > E > e. The EM allele produces a black mask on the muzzle of the dog. This mask can be small and located just around the mouth and nose, or larger and extend up the face and onto the ears. While black dogs may carry the EM allele, only the fawn, wolf sable, and black-and-tan patterns will show the mask. The E allele of MC1R allows for both red and black pigment types to produce the various patterns seen in the breed, though no black mask will be present with this allele. The e allele, when homozygous, produces a solid red coat color with no black hairs. The ee genotype is epistatic to all the ASIP alleles, so a red dog may be carrying any combination of ASIP alleles.

In Eurasiers, the red pigment may be diluted to a cream or silver color. The gene causing of this dilution is not yet known.

GENOTYPES
Please select the color of your dog to determine possible genotypes:
Genotype Main Color Nose Color Hidden Color
EMEayay fawn with mask N/A no mask
EMeayay fawn with mask N/A no mask, red
EMEMayaw fawn with mask N/A wolf sable
EMEayaw fawn with mask N/A no nask, wolf sable
EMeayaw fawn with mask N/A no mask, wolf sable, red
EMEMayat fawn with mask N/A black-and-tan
EMEayat fawn with mask N/A no mask, black-and-tan
EMeayat fawn with mask N/A no mask, black-and-tan, red
EMEMayay fawn with mask N/A none
EMEMaya fawn with mask N/A black
EMEaya fawn with mask N/A no mask, black
EMeaya fawn with mask N/A no mask, black, red
EEayay fawn N/A none
Eeayay fawn N/A red
EEayaw fawn N/A wolf sable
Eeayaw fawn N/A red, wolf sable
EEayat fawn N/A black-and-tan
Eeayat fawn N/A red, black-and-tan
EEaya fawn N/A black
Eeaya fawn N/A black, red
EMEawaw wolf sable with mask N/A no mask
EMeawaw wolf sable with mask N/A no mask, red
EMEMawat wolf sable with mask N/A black-and-tan
EMEawat wolf sable with mask N/A no mask, black-and-tan
EMeawat wolf sable with mask N/A no mask, black-and-tan, red
EMEMawaw wolf sable with mask N/A none
EMEMawa wolf sable with mask N/A black
EMEawa wolf sable with mask N/A no mask, black
EMeawa wolf sable with mask N/A no mask, black, red
EEawaw wolf sable N/A none
Eeawaw wolf sable N/A red
EEawat wolf sable N/A black-and-tan
Eeawat wolf sable N/A balck-and-tan, red
EEawa wolf sable N/A black
Eeawa wolf sable N/A balck, red
EMEMatat black-and-tan with mask N/A none
EMEatat black-and-tan with mask N/A no mask
EMeatat black-and-tan with mask N/A no mask, red
EMEMata black-and-tan with mask N/A black
EMEata black-and-tan with mask N/A balck, no mask
EMeata black-and-tan with mask N/A black, no mask, red
EEatat black-and-tan N/A none
Eeatat black-and-tan N/A red
EEata black-and-tan N/A black
Eeata black-and-tan N/A black, red
EMEMaa black N/A mask
EMEaa black N/A mask. no mask
EMeaa black N/A mask, no mask, red
EEaa black N/A none
Eeaa black N/A red
eeayay red N/A fawn
eeayaw red N/A fawn, wolf sable
eeayat red N/A fawn, black-and-tan
eeaya red N/A fawn. black
eeawaw red N/A wolf sable
eeawat red N/A wolf sable, black-and-tan
eeawa red N/A wolf sable, black
eeatat red N/A black-and-tan
eeata red N/A black-and-tan, black
eeaa white N/A black, red
PRICING
Any single tested allele - $55.00*
Each additional allele - $20.00*
*subject to HST for Canadian residents only.

Note: Mask gene (Em) is considered as an individual test, separate from other alleles in E locus.

To help you to calculate the proper amount, please review the following example:
Testing for 3 alleles - E, B, and D - should be calculated as $55 + $20 + $20 = $95.00.
The price will be automaticaly calculated during the process of ordering a sample collection kit.
SAMPLES
The following sample(s) can be submitted for the testing:
1. Blood sample in a lavender top tube.
2. Cheek swabs. Sample collection kit online: Order a Sample Collection Kit
TEST RESULTS
Test results are usually available in 10 Business Days from the moment the samples arrive at the laboratory. Test results can be reported by e-mail, fax, or by phone.
CERTIFICATE OF RESULT
HealthGene will provide a certificate for each test result.