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Canine Coat and Nose Color Testing

C128-Canine Coat and Nose Color Test
Afghan Hound


Most colors are acceptable in Afghan Hounds in most countries, but nevertheless people have preferences. Because there is such a wide variety of colors in this breed DNA tests are available for most, but not all the genes involved yet. Four E alleles have been shown to exist in Afghans and Salukis. Dogs which are ee can not be brindle or domino or blue or black, even though they may carry the alleles for these colors and patterns at other genes. A black mask only occurs in Afghans that carry at least one EM allele. It is typical for such dogs to have black ear fringe also. Although a mask is not visible on black or blue Afghans, but only on fawn, cream and brindle Afghans, it can be carried by dogs of all these colors. An EG allele is necessary for Afghans to show the pattern known as “domino”. The dominance hierarchy is EM > EG > E > e at this locus.

Afghans have two alleles at the A locus: ay which is dominant or at which is recessive. Dogs with an atat genotype may be black-and-tan, domino, cream or black, depending on the alleles at the E and K loci. Afghans may be red from two different genetic mechanisms. These are virtually indistinguishable when one looks at red dogs. One genotype which causes red is ayat the agouti locus. Because ay is dominant to at, one copy of ay is enough to cause the type of red that is called fawn. Fawn Afghans may or may not have black or brown hair on their ears fringes or along their back. The second genotype which causes a red to cream coat color in Afghans is ee. All of the patterns that include black cannot be produced in dogs that are ee because the mutation in the MC1R gene prevents any eumelanin pigment in hair. However, the nose and pads and eye rims of such dogs can still be black.

All Afghans that are solid black or blue have at least one KB allele. Their other allele may be KB, Kbr, or ky. DNA testing is not yet available to distinguish this second allele. All Afghans that are fawn or black-and-tan or domino, or those that are cream with a mask, are kyky.

Please select the color of your dog to determine possible genotypes:
Genotype Main Color Nose Color Hidden Color
EEatatkyky black-and-tan na none
Eeatatkyky black-and-tan na "clear red"
EGEGatatkyky domino na black-and-tan
EGEatatkyky domino na black-and tan
EGeatatkyky domino na "clear red", black-and-tan
eeayaykyky "clear red" or cream na ay type red or cream
eeayatkyky "clear red" or cream na black-and-tan, ay type red or cream
eeatatkyky "clear red" or cream na black-and-tan
EmEmatatkyky black-and-tan with mask na none
EmEatatkyky black-and-tan with mask na lack of mask
Emeatatkyky black-and-tan with mask na "clear red", lack of mask
EmEGatatkyky black-and-tan with mask na domino, black-and-tan
KB and other alleles black or blue na all other alleles could be present
EEayaykyky ay type red or cream na none
Eeayaykyky ay type red or cream na "clear red"
EEayatkyky ay type red or cream na black-and-tan
Eeayatkyky ay type red or cream na "clear red", black-and-tan
EmEGayaykyky ay type red or cream na domino
EmEmayaykyky ay type red or cream na none
EmEayaykyky ay type red or cream na lack of mask
Emeayaykyky ay type red or cream na "clear red"
EGEGayaykyky ay type red or cream na domino
EGEayaykyky ay type red or cream na domino, lack of mask
EGeayaykyky ay type red or cream na domino, "clear red"
EmEmayatkyky ay type red or cream na black-and tan
EmEGayatkyky ay type red or cream na domino, black-and tan
Emeayatkyky ay type red or cream na "clear red", black-and-tan
EGEGayatkyky ay type red or cream na domino, black-and-tan
EGEayatkyky ay type red or cream na domino, black-and-tan
EGeayatkyky ay type red or cream na "clear red", domino, black-and-tan
EmEayatkyky ay type red or cream na black-and-tan, lack of mask
Any single tested allele - $55.00*
Each additional allele - $20.00*
*subject to HST for Canadian residents only.

Note: Mask gene (Em) is considered as an individual test, separate from other alleles in E locus.

To help you to calculate the proper amount, please review the following example:
Testing for 3 alleles - E, B, and D - should be calculated as $55 + $20 + $20 = $95.00.
The price will be automaticaly calculated during the process of ordering a sample collection kit.
The following sample(s) can be submitted for the testing:
1. Blood sample in a lavender top tube.
2. Cheek swabs. Sample collection kit online: Order a Sample Collection Kit
Test results are usually available in 10 from the moment the samples arrive at the laboratory. Test results can be reported by e-mail, fax, or by phone.
HealthGene will provide a certificate for each test result.