HEALTHGENE´S CANINE BULLETIN (05.30.2005)

IN BRIEF
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MATCHING DOG'S PERSONALITY TO ITS OWNER
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Psychologists at the University of Texas have developed a series of tests to rate a dog's personality. Four factors are reviewed: energy levels, affection – aggression, anxiety – calmness, and intelligence – stupidity. The rating system was adapted from a similar five-factor model used to assess human personality. After conducting a series of tests, Dr. Sam Gosling, a scientist who presented the data, firmly believes that pets should be matched with owners based on similarities in their personalities.
Source: Vetstream.com
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INCREASED HEARTWORM DANGER
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According to the American Heartworm Society (AHS), 27 million dogs in the United States are currently not on a heartworm preventative, needlessly exposing them to potential deadly infection from heartworm.
In 2001, the Gallup survey concluded that only 55 percent of dogs were medicated with heartworm preventative. This is down from 66 percent in 1998. Another study conducted in 2001 on 18,000 veterinary clinics in the United States identified 250,000 dogs and cats tested positive for heartworm infection. Diagnostic tools and medication are available to prevent, identify and treat the infection.
Source: The American Heartworm Society
NOTE: HealthGene Laboratory offers a DNA-based test for heartworm detection that allows for identification with high sensitivity male and female heartworms.
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IF DOGS COULD TALK: EXPLORING THE CANINE MIND
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A new book by a Hungarian ethologist Vilmos Csanyi, "If Dogs Could Talk: Exploring The Canine Mind", uncovers new points of "dogs' smartness". Through a series of experiments with dogs, wolves and their owners over a period of several years, the author demonstrates that dogs "outsmart" not only their relative wolves but also chimpanzees. The abilities to communicate with their owners on different levels are the result of a long history of human-canine co-evolving and something that no other animal has been able to master.
Source: NewScientist.com
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HEALTHGENE'S HIGHLIGHTS
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MAKING SENSE OF COAT COLOR: A GENETIC APPROACH
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This article is intended to help you in understanding the genetics of color. Even though not all aspects can be covered in one article, we will focus on genes that are now available for testing.

The pigment that is responsible for a dog's hair color is called melanin. There are two types of melanin in dogs: a pigment associated with black and brown coloration (called eumelanin) and a pigment associated with lighter colors such as yellow, red and orange (called phaeomelanin). There are a number of genes that affect how and where these pigments are produced. The genes can occur as variant forms, called alleles. Some alleles play a dominant role (usually identified by capital letters) over others and their presence will overshadow the effect of recessive alleles (identified by small letters).

The gene designated as "E" is responsible for eumelanin production. If the dominant form of "E" is not present ("ee" genotype), the black and brown pigment is not produced and the dog's coat will be reddish in color (yellow, orange or red). On the other hand, if at least one E allele ("EE" or "Ee" genotypes) occurs, black or brown pigment would be the basis for a dog's coat color. A third allele, Em, causes reddish dogs to have a black or brown facial mask.

The absence of the dominant form of "B" will change the black color of eumelanin into brown but will have no effect on the coat color of "ee" genotype dogs. For example, dogs with EEBB, EeBB, EeBb genotypes will have eumelanin normally produced ("E" is present) and will have black coat color (the dominant "B" is present). EEbb and Eebb genotypes will have eumelanin produced but their coat will be brown in color ("B" is not present). NOTE: any "bb" genotype dog will have brown nose and pad leather. The eeBB, eeBb, and eebb genotype dogs do not produce eumelanin pigment and will have reddish coat color.

The "A" gene is a bit more complicated. This gene controls where and how two pigments are produced on the body or even on the individual hair. It is very important to understand that the effects of this gene depend on the ability to produce eumelanin, which does not occur in "ee" genotype dogs. The most dominant allele in this group is thought to be ay, which causes sable and fawn coloration of the coat.
Sometimes the reddish hair has black tips. Some examples of this type of dog are sable Collies and Shetland Sheepdogs as well as fawn Great Danes and Pugs. The next allele in dominance is aw, which is characterized by alternately banded hair and sometimes is called "wild type". This type causes hair to change its color during growth from light to dark resulting in bands as seen, for example, in some German Shepherds or wolves.

The black-and-tan allele, at, gives a black dog its tan markings. This is typical of many hounds as well as Rottweilers and Doberman Pinschers. The same allele is responsible for tri-color dogs (black-and-tan with white), for example in Shetland Sheepdogs.

The last allele is a recessive black "a", which is considered to be recessive to all other allele in the "A" group. Such "aa" genotype dogs are black. This can be seen in German Shepherds and Shetland Sheepdogs (bi-color).

There are other groups of genes responsible for coat coloration. They are C (albino), D (blue dilution), G (graying), M (merle), R (roaming), S (white spotting), T (ticking), and K (dominant black). The work of identifying them is still in progress. HeathGene Laboratory would like to thank Dr. Sheila Schmutz from the University of Saskatchewan (Canada) for her dedication and support in this research.
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ARCHIEVES
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HIGHLIGHTS FROM OUR PREVIOUS BULLETINS
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- CANINE BLASTOMYCOSIS (01/19/2005)

- CHRONIC LEPTOSPIROSIS IN DOGS (11/25/2004)

- COAT AND NOSE COLOR TEST IS NOW AVAILABLE FOR NEWFOUNDLAND DOGS
(9/22/2004)

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