CANINE COAT AND NOSE COLOR TEST

CODE: C128

BREED: Afghan Hound

DNA TEST:

All colors are acceptable in Afghan Hounds in most countries, but nevertheless people have preferences. DNA testing for the E alleles in Afghan Hounds allows breeders to better predict the colors of pups from particular matings. All 3 E alleles have been shown to exist in Afghans.
Afghans may be red from two different genetic mechanisms. These are virtually indistinguishable when one looks at red dogs. One genotype which causes red is ay at the agouti locus, as demonstrated by Claudia in the link below. Because ay is dominant to most or all other alleles at this locus, one copy is enough to cause the type of red that some breeds call fawn. Such red dogs are E_, ay or Em_, ay depending on whether or not they have a mask.
The second genotype which causes a red coat color in Afghans is ee. This may be more rare but we have not tested enough dogs to be sure of this yet. Dogs which are "ee" can not be brindle or domino, even though they may carry the alleles for these patterns at other genes. They also never have a mask. All of the patterns that include black and black pigment can not be produced in dogs that are "ee" because the mutation in the MC1R gene prevents any eumelanin pigment in hair. However, the nose and pads and eye rims of such dogs can still be black.
A black mask only occurs in Afghans that carry at least one Em allele. It is typical for such dogs to have black ear fringe also. Although a mask is not visible on black or blue Afghans but only on fawn, cream and brindle Afghans, it can occur in dogs of all these colors. Kaschmir, at the top, is cream because he is a dilute red but he has a striking black mask. Em is the "top dominant" allele in this series.
Although Little (1957) suggested that ebr was another allele in this series that caused brindle, recent DNA studies prove that brindle is caused by another gene instead.

LINKS:

Dr.Schmutz's Webpage For Color Mutations in Afgan Hounds

GENOTYPES:

Genotypes

Coat Color

Hidden Color

EmEmayay

black or blue, brindle, or ay type red or cream with mask

-

EmEayay

black or blue, brindle, or ay type red or cream with mask

lack of mask

Emeayay

black or blue, brindle, or ay type red or cream with mask

"clear red", lack of mask

EEayay

black or blue, brindle, or ay type red or cream

-

Eeayay

black or blue, brindle, or ay type red or cream

"clear red"

eeayay

"clear red" or cream

-

EmEmayat

black or blue, brindle, or ay type red or cream with maskwith mask

black-and-tan

EmEayat

black or blue, brindle, or ay type red or cream with mask with mask

black-and-tan, lack of mask

Emeayat

black or blue, brindle, or ay type red or cream with mask

"clear red", black-and-tan, lack of mask

EEayat

black or blue, brindle, or ay type red or cream

black-and-tan

Eeayat

black or blue, brindle, or ay type red or cream

"clear red", black-and-tan

eeayat

"clear red" or cream

black-and-tan

EmEmatat

black or blue, brindle, or ay type red or cream with mask

-

EmEatat

black or blue, brindle, or ay type red or cream with mask

lack of mask

Emeatat

black or blue, brindle, or ay type red or cream with mask

"clear red", lack of mask

EEatat

black or blue, brindle, or ay type red or cream with mask

-

Eeatat

black or blue, brindle, or ay type red or cream with mask

"clear red"

eeatat

"clear red" or cream

-

PRICE:

- $105.00 *
Special contract prices are available for Breeder Clubs. Please, contact us for more information.
*- subject to the applicable taxes (5% GST Canadian Residents only) 


SAMPLES:

Two types of samples can be submitted for this DNA test:
- A blood sample in a lavender (EDTA) tube;
- Cheek swabs  - Order a Sample Collection Kit!

TEST RESULTS:

Test results are usually available in 10 business days from the moment the samples arrive at the laboratory. Test results can be reported by e-mail, fax, or by phone.

CERTIFICATION OF RESULTS:
HealthGene will provide a certificate for each test result



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